100 Years Biochemical Sciences Tutorial

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Tag: Publication

A ROTARY MOTOR FOR BACTERIAL GLIDING [BERG LAB]

(l to r) Howard Berg, Abhishek Shrivastava, and Pushkar Lele Bacterial gliding is defined as steady movement over a surface, of bacteria that have neither flagella nor pili. …

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ONE SMALL TWEAK CONVERTS A TRANSPORTER FROM A ONE-WAY INTO A TWO-WAY STREET [GAUDET LAB]

Ahmet Vakkasoglu (l) and Rachelle Gaudet At the heart of our adaptive immune system is the presentation of internal antigens, usually peptides, to cytotoxic T cells. The Transporter…

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LIS1 [LESCHZINER LAB]

(l to r) Kat Toropova, Andres Leschziner,Sam Reck-Peterson, Sirui Zou and  (front row) Locksley Cytoskeletal motors are molecular machines that “walk” along the filaments that provide structural support…

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RNA REMODELING BY AN EFFICIENT RETROVIRAL RENOVATOR [D’SOUZA LAB]

As anyone who has renovated a home knows, the process of remodeling often requires an elaborate orchestration of timing and materials. Remodeling at the molecular level is likewise…

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BUILDING A CLUB SANDWICH [SANES LAB]

The aim of developmental neurobiology is to learn how the nervous system is built, and to find the developmental anomalies that are thought to underlie some brain diseases. …

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PARTNERS FOR LIFE [SANES LAB]

Neurons form precise relationships with particular synaptic partners and these relationships give rise to the wiring diagram that enables cognitive function. Like other partnerships, neural connections need to…

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INPUTOME OF DOPAMINE AND SEROTONIN NEURONS [UCHIDA LAB]

(l to r) Sachie K. Ogawa, Mitsuko Watabe-Uchida, and Nao Uchida When I told my niece in medical school that I am studying dopamine, she looked surprised, asking,…

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DETECTION OF TARGET ODORS FROM MIXTURES [MURTHY LAB]

Natural environments are rich with sensory stimuli. To make sense of the sensory clutter, animals must segregate objects of interest from ever varying backgrounds. Our visual system is…

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COUPLING TRANSCRIPTION AND TRANSLATION IN EUKARYOTES [O’SHEA LAB]

Erin O'Shea (l) and Brian Zid The central dogma of molecular biology proposes that information flows from DNA to RNA through the process of transcription and from RNA…

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RESCUING SENSORY INTEGRATION IN MOUSE MODELS OF AUTISM [HENSCH LAB]

Many people with autism display atypical sensory processing, and in independent studies, abnormalities in a deep brain structure known as the insula. A new study from researchers at…

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