100 Years Biochemical Sciences Tutorial
Left to right: Michael J. Rust, Erin K. O'Shea, and Joseph S. Markson Circadian rhythms are daily cycles of behavior and metabolism that allow organisms to anticipate the…
Authors Wen-Yee Choi, Antonio Giraldez (on screen), and Alex Schier MicroRNAs are small RNAs that bind to specific mRNAs and inhibit their translation. Hundreds of microRNAs are thought…
Perhaps you have had the experience of walking into a new environment, such as a Moroccan bazaar or a Chinese supermarket for the first time, and being struck…
Authors Jennings Xu, Catherine Dulac, and Tali Kimchi In rodents, as in most vertebrates, the social and sexual behaviors of males and females clearly differ. For example, female…
Jiangwen Zhang, Monica Carrasco, Eugene Makeyev and Tom Maniatis Cellular differentiation requires global changes in gene expression at both transcriptional and posttranscriptional levels. Posttranscriptional regulation provides a mechanism…
Authors Ben Allen (left) and Andy McMahon Hedgehog (Hh) proteins are secreted morphogens that act in a concentration depependent manner to shape numerous developmental processes. The effects of…
This illustration is a surface representation of the TRPV1ankyrin repeat structure (in green) with a bound ATP molecule (multicolor sticks) on a background of capsaicin-laden red pepper flakes.…
L to R: Garrett Birkhoff, Dieter Egli, Jacqueline Rosains and Kevin Eggan Ten years ago, the cloning of Dolly the sheep confirmed that the mamalian egg (oocyte), possesses…
(L to R): Jochen Utikal, Matthias Stadtfeld, Nimet Maherali, Konrad Hochedlinger, Sarah Eminli, and Katrin Arnold Nuclear transfer experiments, such as the cloning of Dolly the sheep, have…
Co-authors (left to right): Hongkai Ji, Steven Vokes, Andrew McMahon and Wing H. Wong The Hedgehog signaling pathway represents one of approximately six major families of signaling pathways…
