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Dendrites are the antennae of neurons, receiving synaptic signals from other neurons. A critical aspect of wiring up complex neural circuits is to make sure that dendrites are…
Neural circuits in the mammalian brain comprise hundreds to millions of neurons, connected with each other in complex and highly specific ways. Studies over the past few decades…
The dendritic arbors of neurons are incredibly diverse in size and shape. This makes sense, because dendritic morphology is a critical determinant of the numbers and types of…
MCB professor Joshua Sanes has won this year’s Gruber Neuroscience Prize; a valuable international award given by the Society for Neuroscience and funded by Yale University’s Gruber Foundation.…
As neurons develop in the central nervous system, they encounter many potential synaptic partners, and choose among them to form stable connections with only a few. The specific…
The complex circuits of the brain are built from thousands of types of neurons. More than a century ago, Santiago Ramon y Cajal founded what we now call…
Neurons connect with each other to form complex circuits that underlie mental activities. Mapping these connections to obtain a so-called wiring diagram is an essential step in learning…
The retina is not only a light sensor but also a sophisticated image processor. Photoreceptors (rods and cones) generate electrical signals when illuminated, much like pixels in a…
Joshua Sanes contributes optimism (and a great deal of research) to an August 7 Science magazine article on the longstanding controversy of neuronal classification. While skeptics suspect we…
Joshua Sanes (l) and Dimitar Kostadinov The dendritic processes of neurons form elaborate branched arbors that are stereotyped among neurons of a specific type but differ markedly among…
