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The neuromuscular junction on the top is from a young adult mouse; that on the bottom from an 2-year old mouse, which is quite old for a mouse.…
(L to right) Gregorio Valdez and Joshua R. Sanes The great baseball player, Lou Gehrig, gave his name to the neurodegenerative disease that killed him, Amyotrophic Lateral Sclerosis.…
Co-authors (L to R) Yifeng Zhang, Markus Meister, Joshua R. Sanes, In-Jung Kim, and Masahito Yamagata, A mouse is small, close to the ground. Hawks and cats may…
The co-authors (left to right): Ju Lu, Jeff W. Lichtman, Jean Livet, Joshua R. Sanes, Tamily A. Weissman, Ryan W. Draft, Hyuno Kang More than a century ago,…
Authors Josh Sanes (left) and Brendan Lilley Directional flow of information within the nervous system depends upon the ability of neurons to divide themselves into discrete compartments. Most…
From L to R: Ann Pearson, Michael Brenner, Reid Leonard of Merck, Craig Hunter, Brian Chen, Iftach Nachman, and Catherine Dulac The recipients of the 2007 Merck Genome-Related…
Authors Michael Fox (left) and Josh Sanes The synapse is the heart of the nervous system, the site at which information is processed and passed between cells. Proper…
First-author Florence Bareyre A tragic truth is that the mammalian central nervous system (CNS) has very limited ability to regenerate following injury. There is intense interest in trying…
Development paper MCB authors Josh Sanes and Michael Fox The synapse is the heart of the nervous system, the site at which information is processed and passed between…
A recent study by Kishi et al. shows how research programs can take unexpected directions. The authors wanted to study how small parts of neuronal processes become specialized…
