Many of the approved chemotherapy drugs are either collected from natural sources or inspired by molecules existing in nature. Natural products with anticancer activity can be readily identified…
Tag: Publication
A MULTI-LAYERED NEURAL COMPUTATION FOR SIMPLE ARITHMETIC [UCHIDA LAB]
An exciting aspect of neuroscience is the ability to peek into the brain, measuring the activity of neurons in behaving animals. Electrophysiology allows us to listen to the…
A SOLUTION TO THE OLFACTORY COCKTAIL PARTY PROBLEM [MURTHY LAB]
How good are we at detecting a specific smell in a mixture of smells – for example, the fragrance of a stargazer lily in a large bouquet of…
PANNING FOR PRECIOUS METALS [GAUDET LAB]
When we think of the chemical elements of life, the “big four” of carbon, oxygen, nitrogen, and hydrogen leap to mind, and rightly so, as they make up…
STAMP COLLECTING GETS IMPORTANT [SANES LAB]
The complex circuits of the brain are built from thousands of types of neurons. More than a century ago, Santiago Ramon y Cajal founded what we now call…
DECIPHERING PROTEIN INTERFACES THAT HELP WIRE THE BRAIN [GAUDET LAB]
During brain development, neurons connect with each other using branched projections called dendrites. As a dendrite extends away from its neuron’s cell body to connect with dendrites from…
RECONSTRUCTION OF GENETICALLY IDENTIFIED NEURONS IMAGED BY SERIAL-SECTION ELECTRON MICROSCOPY [SANES AND LICHTMAN LABS]
Neurons connect with each other to form complex circuits that underlie mental activities. Mapping these connections to obtain a so-called wiring diagram is an essential step in learning…
TURNING UP THE HEAT ON PROTEIN FOLDING BY TURNING DOWN HEAT SHOCK FACTOR [DENIC LAB]
(l to r) David Pincus, Eric Solís, Vlad Denic No matter where you fall on the spectrum of libertarianism this election year, you can hopefully appreciate that the…
CRISPR CELL LINEAGES [SCHIER LAB]
The cells in a multicellular organism develop via a lineage that starts with the fertilized egg. Lineage trees describe the divisions and specializations of cells over time, as…
PERSISTENCE REWARDED [BERG LAB]
I have been intrigued by bacterial flagellar motors since 1973, when Bob Anderson and I argued that bacterial flagellar filaments are rigid helices driven at their base, rather…
