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Tag: Publication

Unusual Calcium Binding Allows Flexing of a Cadherin Involved in Hearing [Gaudet Lab]

Vertebrates rely on the inner ear to convert the mechanical stimuli of sound and head movements into electrical signals that can be decoded by the brain. This process,…

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Inheritance of Epigenetic Information [Hunter Lab]

RNA interference (RNAi) in C. elegans is remarkably potent and efficient.  It is potent because minuscule amounts of RNA silencing signals can be amplified and it is efficient…

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WHAT’S ON THE NEWS? DOPAMINE BROADCASTS MULTIPLE TYPES OF INFORMATION [Uchida Lab]

Monoamine neurotransmitters such as dopamine, serotonin, and noradrenaline are released by small populations of neurons that send information to much of the brain. These neurons function like major…

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INSIGHTS INTO CAUSES OF ANEMIA FROM A MEMBRANE PROTEIN STRUCTURE [GAUDET LAB]

Iron is a key micronutrient that organisms use in many biological processes. Indeed, aerobic respiration requires iron to transport oxygen in our blood, to catalyze redox reactions of…

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NEW STRUCTURAL RNAS? NOW WE CAN TELL [RIVAS AND EDDY LABS]

Some fundamental cellular activities are directed by RNA-based machines. The RNAs in these machines adopt distinct three-dimensional structures in order to facilitate their function, much in the way…

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NEURAL CIRCUITS AT THE BRAIN SCALE [ENGERT LAB]

A longstanding goal of neuroscience is to figure out how the brain reacts to what is happening in the outside world. But it has been challenging to map…

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HOW A MAMMAL GOT ITS STRIPES [HOEKSTRA LAB]

by the astonishing variety of forms, shapes, and colors that have evolved in nature. This variation has allowed organisms to adapt to their local environments, for example, to…

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FINDING FORKS IN THE ROAD OF HUMAN BRAIN DEVELOPMENT [RAMANATHAN LAB]

Human brain cells begin their lives as pluripotent cells with the potential to develop into any cell type in the body. As those pluripotent stem cells differentiate and…

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COMMON CURRENCY FOR REWARD AND PUNISHMENT [UCHIDA LAB]

Considering both good and bad is fundamental for future planning and decision-making. When animals forage, they may consider how tasty the food is, how much food is available…

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MOLECULAR COMPETITION ENHANCES SYNAPTIC SPECIFICITY [SANES LAB]

As neurons develop in the central nervous system, they encounter many potential synaptic partners, and choose among them to form stable connections with only a few. The specific…

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