100 Years Biochemical Sciences Tutorial
Seung-Hwan Kim and Matthew Michael Just as dinner party guests who linger at the table long after coffee and dessert can strain the patience of their hosts, an…
(L to R) Andy McMahon and Jan Stenman All tissues in our bodies require blood vessels for oxygen and nutrients. While all vasculature share certain features, their formation…
Andrew Capaldi and Erin O'Shea The gene expression program in a cell is set in response to the level, timing and combination of hundreds of developmental and environmental…
Erin O'Shea, and Harold Kim One of the main challenges in the postgenomic era is to understand how genetic information is translated into quantitative transcriptional output. Transcription factors…
Co-authors (left to right): Hongkai Ji, Steven Vokes, Andrew McMahon and Wing H. Wong The vertebrate limb has been one of the central models for understanding the problem…
Many regions of the brain are organized in such a way that they form an ordered representation of our sensory experiences. Similar physical stimuli –nearby points of light…
(left panel) Monocular retinal innervation in a normal larval zebrafish. The right optic tectal lobe receives input solely from the contralateral (red) retina. (right panel) Following rewiring, the…
(L to R) Sayaka Sugiyama and Takao Hensch Researchers have long sought a factor that can trigger the brain’s ability to learn – and perhaps recapture the “sponge-like”…
(L to R) Andy McMahon, Todd Valerius, Josh Mugford, and Akio Kobayashi The kidney is a remarkable organ. Its actions maintain an appropriate water/salt balance within tissue fluids,…
The co-authors (left to right): M. Prentiss, R. Koszul, K.P. Kim, S. Kameoka, and N. Kleckner Movement plays important fundamental roles in basic chromosomal processes. Motion is most…
