100 Years Biochemical Sciences Tutorial
In 2007, the labs of Professors Jeff Lichtman and Josh Sanes introduced a multicolor labeling strategy called “Brainbow.” It involves use of transgenic mice in which various combinations…
(l to r) Sophie de Buyl, Shu-Wen Teng, Jeffrey R. Moffitt, and Shankar Mukherji with Nikhil Living organisms tightly coordinate their physiology with the day and night cycle.…
(l to r) Guillaume Witz, Mara Prentiss, Nancy Kleckner, Beth Weiner, and Jay K. Fisher The E. coli chromosome is a single circular unit which, if stretched out,…
How many decisions did you have to make today? From the choice of breakfast, to the vigor of brushing our teeth, we can effortlessly make moment to moment…
John Koschwanez (l) and Andrew Murray How do microbes evolve to utilize nutrients that they can't import? We used engineering and experimental evolution of budding yeast to study…
Erin O'Shea (l) and Andrian Gutu The day-night cycle is the most predictable environmental variation on Earth. Many organisms, ranging from bacteria to humans have evolved endogenous time-keeping…
In recent years, a growing number of studies have reported the identity of genes that contribute to phenotypic variation. However, few have narrowed the causative effects down to…
What is the function of a sensory system? One straightforward idea is that it strives to create a complete and accurate internal representation of the external world, which…
(L to R) Sirui Zou, Bret Redwine, Andres Leschziner, Rogelio Hernandez-Lopez, and Samara Reck-Peterson, front row Locksley Walking takes an enormous amount of coordination. As your leading foot…
(L to R) Dimitar Kostadinov, Joshua Sanes, and Julie Lefebvre Neurons in the brain extend elaborately branched dendrites that receive inputs from other neurons and sensory stimuli. In…
