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PARENTAL CONFLICTS IN THE BRAIN

Christopher Gregg and Catherine Dulac Parents influence the brain development and the behavior of their offspring in extraordinary and varied ways that impact the success of their offspring…

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A SMALL MOLECULE TRIGGER FOR BIOFILM DISASSEMBLY

A three-way collaboration between the laboratories of Rich Losick in MCB and Roberto Kolter and Jon Clardy at Harvard Medical School has led to the discovery of a…

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MOLECULAR MECHANICS OF HEARING AND DEAFNESS

Cadherin-23 stretching simulations. A close-up view of the linker region between cadherin-23 repeats 1 and 2 is shown during a molecular dynamics simulation in which the protein is…

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THE CHROMATIN SIGNATURE OF PLURIPOTENT CELLS

(L to R)Nadine Vastenhouw and Alexander Schier The genomes of most animals are inactive for hours or days after fertilization. Transcription is only initiated during the maternal-zygotic transition…

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PREDICTING DRUG TARGETS BY WATCHING ZEBRAFISH SLEEP

(L to R)Alexander Schier and Jason Rihel Many psychiatric drugs were discovered decades ago through serendipity. For example, a tuberculosis drug called iproniazid also happened to make people…

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A ROLE FOR MICRORNAS IN AMYOTROPHIC LATERAL SCLEROSIS

(L to right) Gregorio Valdez and Joshua R. Sanes The great baseball player, Lou Gehrig, gave his name to the neurodegenerative disease that killed him, Amyotrophic Lateral Sclerosis.…

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GABA NEURONS TURN A BLIND EYE

Takao Hensch A new study, published in this week's Nature, that helps tease apart the role of single cells in the neural circuit controlling vision is helping researchers…

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